Nutrition

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Sunday, April 13, 2008
Nutrition and its Uses
Nutrition and its Uses
Nutrition is the provision, to cells and organisms, of the materials necessary (in the form of food) to support life. Many common health problems can be prevented or alleviated with good nutrition.
Nutritional science
Nutritional science investigates the metabolic and physiological responses of the body to diet. With advances in the fields of molecular biology, biochemistry, and genetics, the study of nutrition is increasingly concerned with metabolism and metabolic pathways, the sequences of biochemical steps through which the many substances of living things change from one form to another.
The human body contains chemical compounds, such as water, carbohydrates (sugar, starch, and fiber), amino acids (in proteins), fatty acids (in lipids), and nucleic acids (DNA/RNA). These compounds, in turn, consist of elements such as carbon, hydrogen, oxygen, nitrogen, phosphorus, calcium, iron, zinc, magnesium, manganese, and so on. All of these chemical compounds and elements occur in various forms and combinations (e.g. hormones/vitamins, phospholipids, hydroxyapatite), both in the human body and in organisms (e.g. plants, animals) that humans eat.
In a typical adult, about seven liters of digestive juices enter the lumen of the digestive tract. They break chemical bonds in ingested molecules and modulate their conformations and energy states.
Though some molecules are absorbed into the bloodstream unchanged, digestive processes release them from the matrix of foods in which they occur. Unabsorbed matter is excreted in the feces.
Nutrients and its classes
The major classes of nutrients: carbohydrates, fats, fiber, minerals, proteins, vitamins, and water.
These nutrient classes can be generally grouped into the categories of macronutrients (needed in relatively large amounts), and micronutrients (needed in smaller quantities). The macronutrients are carbohydrates, fats, fiber, proteins and water. The other nutrient classes are micronutrients.
The macronutrients (excluding fiber and water) provide energy, which is highly used to measured in kilocalories, often called "Calories" and written with a capital C to distinguish them from small calories. Carbohydrates and proteins provide four (4) Calories of energy per gram, while fats provide nine (9) Calories per gram. Vitamins, minerals, fiber, and water do not provide energy, but are necessary for other reasons.
Molecules of carbohydrates and fats consist of carbon, hydrogen, and oxygen atoms. Protein molecules contain nitrogen atoms in addition to carbon, hydrogen, and oxygen. The nitrogen includes the components of protein, called amino acids, fulfill many roles other than energy metabolism, and when they are used as fuel, getting rid of the nitrogen places a burden on the kidneys. Other micronutrients not categorized above include antioxidants, essential fatty acids, and phytochemicals.
Carbohydrates
Carbohydrates can be classified as monosaccharides, disaccharides, or polysaccharides by the number of sugar units they contain. Monosaccharides contain 1 sugar unit, disaccharides contain 2, and polysaccharides contain 3 or more. Polysaccharides are often referred to as complex carbohydrates because they are long chains of sugar units, whereas monosaccharides and disaccharides are simple carbohydrates. Simple carbohydrates are metabolized quickly and thus raise blood sugar levels more quickly resulting in rapid increases in blood insulin levels compared to complex carbohydrates.
Fat
Fats are combination of fatty acids (long carbon/hydrogen chains) bonded to a glycerol. Fat can be classified as saturated or unsaturated. Saturated fats have all of their carbon atoms bonded to hydrogen atoms, whereas unsaturated fats have some of their carbon atoms double-bonded in place of a hydrogen atom. Generally, saturated fat is solid at room temperature while unsaturated fat is a liquid.
The unsaturated fats can be further classified as mono-unsaturated (one double-bond) or poly-unsaturated (many double-bonds). Trans fats are saturated fats which are typically created from unsaturated fat by adding the extra hydrogen atoms in a process called hydrogenation (also called hydrogenated fat).
Fiber
Dietary fiber consists of cellulose that is indigestible because we do not have enzymes to digest it. Fruits and vegetables are rich in dietary fiber.
Uses:
1.Provides bulk to the intestinal contents
2.Stimulates peristalsis (rhythmic muscular contractions passing along the digestive tract)
Note:
Lack of dietary fiber in the diet leads to constipation (failure to pass motions).
Protein
Most of the meats such as chicken contain all the essential amino acids needed for humans.
Protein is a mixture of amino acids, that are body's structural (muscles, skin, hair etc.) materials. The body requires amino acids to produce new body protein (protein retention) and to replace damaged proteins (maintenance) that are lost in the urine. In animals amino acid requirements are classified in terms of essential (an animal cannot produce them) and non-essential (the animal can produce them from other nitrogen containing compounds) amino acids.
Dietary sources of protein consists of meats, eggs, grains, legumes, and dairy products such as milk and cheese. Proteins can be converted into carbohydrates through a process called gluconeogenesis.
Minerals
The dietary minerals are the chemical elements required by living organisms, other than the four elements carbon, hydrogen, nitrogen, and oxygen which are present in common organic molecules.
Some dietitians recommend that these heavier elements should be supplied by ingesting specific foods (that are enriched in the element(s) of interest), compounds, and sometimes including even minerals, such as calcium carbonate. Sometimes these "minerals" come from natural sources such as ground oyster shells. Sometimes minerals are added to the diet separately from food, such as mineral supplements, the most famous being iodine in "iodized salt."
Macro minerals
Many elements are required to support the biochemical processes, many play a role as electrolytes or in a structural role.
In Human nutrition, the dietary bulk "mineral elements" (RDA > 200 mg/day) are in alphabetical order (parenthetical comments on folk medicine perspective) they are,
1.Calcium (for muscle and digestive system health, builds bone, neutralizes acidity, clears toxins, helps blood stream)
2.Chloride
3.Magnesium required for processing ATP and related reactions (health, builds bone, causes strong peristalsis, increases flexibility, increases alkalinity)
4.Phosphorus required component of bones (see apatite) and energy processing and many other functions (bone mineralization)[3]
5.Potassium required electrolyte (heart and nerves health)
6.Sodium electrolyte
7.Sulfur for three essential amino acids and many proteins and cofactors (skin, hair, nails, liver, and pancreas health).
Trace minerals
Selenium is essential for peroxidase (antioxidant a variety of elements are required in trace amounts, unusually because they play a role in catalysis in enzymes. Some trace mineral elements (RDA <>Cobalt required for biosynthesis of vitamin B12 family of coenzymes
2.Copper required component of many redox enzymes, including cytochrome c oxidase
3.Chromium required for sugar metabolism
4.Iodine required for the biosynthesis of thyroxin
5.Iron required for many proteins and enzymes, notably hemoglobin
6.Manganese (processing of oxygen)
7.Molybdenum required for xanthine oxidaseproteins)
8.Vanadium (There is no established RDA for vanadium. No specific biochemical function has been identified for it in humans, although vanadium is found in lower organisms.)
9.Zinc required for several enzymes such as carboxypeptidase, liver alcohol dehydrogenase, carbonic anhydrase. Zinc is pervasive.
Iodine is required in larger quantities than the other trace minerals in this list and is sometimes classified with the bulk minerals. Sodium is not generally found in dietary supplements, despite being needed in large quantities, because the ion is very common in food.
Vitamins
Mineral and vitamin deficiency or excess may yield symptoms of diminishing the health such as goitre, scurvy, osteoporosis, weak immune system, disorders of cell metabolism, certain forms of cancer, symptoms of premature aging, and poor psychological health (including eating disorders), among many others.
Moreover, thousands of different phytochemicals have recently been discovered in food (particularly in fresh vegetables), which have many known and yet to be explored properties including antioxidant activity (see below). Other essential nutrients include essential amino acids, choline and the essential fatty acids.
Water
For the proper function the body requires between one and seven liters of water per day to avoid dehydration; the precise amount depends on the level of activity, temperature, humidity, and other factors. With physical exertion and heat exposure, water loss will increase and daily fluid needs may increase as well.
The water intake is very essential. For the healthy people, although some experts assert that 8–10 glasses of water (approximately 2 liters) daily is the minimum to maintain proper hydration.
The original recommendation for water intake in 1945 by the Food and Nutrition Board of the National Research Council read: "An ordinary standard for diverse persons is 1 milliliter for each calorie of food. Most of this quantity is contained in prepared foods. The latest dietary reference intake report by the United States National Research Council in general recommended (including food sources): 2.7 liters of water total for women and 3.7 liters for men. Specifically, pregnant and breastfeeding women need additional fluids to stay hydrated. According to the Institute of Medicine—who recommend that, on average, women consume 2.2 litres and men 3.0 litres—this is recommended to be 2.4 litres (approx. 9 cups) for pregnant women and 3 litres (approx. 12.5 cups) for breastfeeding women since an especially large amount of fluid is lost during nursing.
Generally, about 20 percent of water intake comes from food, while the rest comes from drinking water and beverages (caffeinated included). Water is excreted from the body in multiple forms; through urine and feces, through sweating, and by exhalation of water vapor in the breath.
Other nutrients
Other nutrients consists of antioxidants, essential fatty acids, and phytochemicals. These substances are generally more recent discoveries which: have not yet been recognized as vitamins; are still under investigation; or contribute to health but are not necessary for life. Phytochemicals may act as antioxidants, but not all phytochemicals are antioxidants.
Antioxidants
The cellular metabolism/energy production requires oxygen, potentially damaging (e.g. mutation causing) compounds known as radical oxygen species or free radicals form as a result. For normal cellular maintenance, growth, and division, these free radicals must be sufficiently neutralized by antioxidant compounds, some produced by the body with adequate precursors (glutathione, Vitamin C in most animals) and those that the body cannot produce may only be obtained through the diet through direct sources (Vitamin C in humans, Vitamin A, Vitamin K) or produced by the body from other compounds (Beta-carotene converted to Vitamin A by the body, Vitamin D synthesized from cholesterol by sunlight). Phytochemicals (Section Below) and their subgroup polyphenols comprise of the majority of antioxidants, some 4,000 known, and therefore there is much overlap. Different antioxidants are now known to function in a cooperative network, e.g. vitamin C can reactivate free radical-containing glutathione or vitamin E by accepting the free radical itself, and so on.
Essential fatty acids
Mostly the fatty acids are non-essential, meaning the body can produce them as needed, however, at least two fatty acids are essential and must be consumed in the diet. An appropriate balance of essential fatty acids - omega-3 and omega-6 fatty acids - has been discovered to be important for maintaining health. Both of these unique "omega" long-chain polyunsaturated fatty acids are substrates for a class of eicosanoids known as prostaglandins which function as hormones.
The rate of conversions of omega-6 DGLA to AA largely determines the production of the respective prostaglandins PGE1 and PGE2. Omega-3 EPA prevents AA from being released from membranes, thereby skewing prostaglandin balance away from pro-inflammatory PGE2 made from AA toward anti-inflammatory PGE1 made from DGLA. Moreover, the conversion (desaturation) of DGLA to AA is controlled by the enzyme delta-5-desaturase, which in turn is controlled by hormones such as insulin (up-regulation) and glucagon (down-regulation).
Phytochemicals
The growing area of interest is the effect upon human health of trace chemicals, collectively called phytochemicals. This kind of nutrients are typically found in edible plants, especially colorful fruits and vegetables, but also other organisms including seafood, algae, and fungi. The effects of phytochemicals increasingly survive rigorous testing by prominent health organizations. One of the principal classes of phytochemicals are polyphenol antioxidants, chemicals which are known to provide certain health benefits to the cardiovascular system and immune system. These chemicals are known to down-regulate the formation of reactive oxygen species, key chemicals in cardiovascular disease.
Diet (nutrition)
The nutrition and the diet is the sum of food consumed by a person or other organism. Dietary habits are the habitual decisions an individual or culture makes when choosing what foods to eat. Although humans are omnivores, each culture holds some food preferences and some food taboos. Individual dietary choices may be more or less healthy. Proper nutrition requires the proper ingestion and equally important, the absorption of vitamins, minerals, and fuel in the form of carbohydrates, proteins, and fats. Dietary habits and choices play a significant role in health and mortality, and can also define cultures and play a role in religion.
Religious and cultural dietary choices
The cultures and religions have restrictions concerning what foods are acceptable in their diet. For example, only Kosher foods are permitted by Judaism, and Halal foods by Islam.
Diets for weight management
The diet may be chosen to seek weight gain, weight loss, sports training, cardio-vascular health, avoidance of cancers, food allergies and for other reasons. Changing a subject's dietary intake, or "going on a diet", can change the energy balance and increase or decrease the amount of fat stored by the body. Some kind of foods are specifically recommended, or even altered, for conformity to the requirements of a particular diet. These diets are often recommended in conjunction with exercise.
Eating disorders
An eating disorder is a mental disorder that interferes with normal food consumption. Eating disorders often affect people with a negative body image.
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